Can RNA/DNA be measured?
Yes, by applying a PLL (poly L-lysine) or APTES (3-Triethoxysilylpropylamine) coating to the glass. Nucleic acids do not bind to untreated glass because of their negative charge.
For further information, see our application note on mass photometry of nucleic acids (https://www.refeyn.com/mass-photometry-of-nucleic-acids).
144 Views