Mass Photometry on IDPs
Hello, I am starting a new project with a protein that has extensive intrinsically unstructured regions. What are the experiences of the community with this? I am searching for good references. I know it should be possible, but I am struggling to find literature references where authors did this. Thank you.
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HI Annette,
You can use the Feature Publication search (Resources: Publications - Refeyn) to look up keywords on proteins with IDR. Here are some preliminary search from using the tool:
Structural basis of Spliced Leader RNA recognition by the Trypanosoma brucei cap-binding complex - PMC
Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes | Nature Communications
Mechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination | Nature Communications
Happy to help if you have more questions
Amy Chau
Sr. Field Applications Scientist